BDBM50333127 (beta-D-2',3'-dideoxy-5'-F-cytidine-5'-triphosphate)::CHEMBL1630222

SMILES Nc1ccn([C@H]2CC[C@H](O2)[C@@H](F)OP(O)(=O)OP(O)(=O)OP(O)(O)=O)c(=O)n1

InChI Key InChIKey=XWDUBJCSVAGKQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50333127   

TargetDNA polymerase subunit gamma-1(Human)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50333127((beta-D-2',3'-dideoxy-5'-F-cytidine-5'-triphosphat...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human DNA polymerase gamma assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetDNA polymerase alpha catalytic subunit(Human)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50333127((beta-D-2',3'-dideoxy-5'-F-cytidine-5'-triphosphat...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human DNA polymerase alpha assessed as incorporation of [alpha-32P]dCTP up to 1mM preincubated for 30 mins by whatman DE81 paper bindin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed