BDBM50333419 7-(Cyclohexylmethoxy)-1-methyl-beta-carboline::CHEMBL1645548

SMILES Cc1nccc2c3ccc(OCC4CCCCC4)cc3[nH]c12

InChI Key InChIKey=XPNBZXYLKBNCSU-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333419   

TargetAmine oxidase [flavin-containing] A(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50333419(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline | CH...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50333419(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline | CH...)
Affinity DataIC50: 220nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50333419(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline | CH...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL
LigandPNGBDBM50333419(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline | CH...)
Affinity DataKi:  222nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed