BDBM50333441 4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)piperidine::CHEMBL1645608

SMILES Fc1cccc(Oc2c(F)cccc2Cl)c1OC1CCNCC1

InChI Key InChIKey=LGPYPLZSWZJHBL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333441   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333441(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
LigandPNGBDBM50333441(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)
Affinity DataKi:  218nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333441(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)
Affinity DataKi:  2.04E+3nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333441(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)
Affinity DataKi: >6.37E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed