BDBM50333559 3-Chloro-2-{5-chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]-pyrimidine-4-ylamino}-N-methyl-benzamide::CHEMBL1642133

SMILES CNC(=O)c1cccc(Cl)c1Nc1nc(Nc2ccc3CCN(CCOC)CCc3c2)ncc1Cl

InChI Key InChIKey=ISCFWDSEWHMZOJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333559   

TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333559(3-Chloro-2-{5-chloro-2-[3-(2-methoxy-ethyl)-2,3,4,...)
Affinity DataIC50: 550nMAssay Description:Inhibition of c-Met expressed in human GTL-16 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333559(3-Chloro-2-{5-chloro-2-[3-(2-methoxy-ethyl)-2,3,4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333559(3-Chloro-2-{5-chloro-2-[3-(2-methoxy-ethyl)-2,3,4,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed