BDBM50333563 3-[5-Chloro-4-(2-fluoro-6-methylcarbamoyl-phenylamino)-pyrimidin-2-ylamino]-7,8-dihydro-6H-5-oxa-9-aza-benzocycloheptene-9-carboxylic acid ethyl ester::CHEMBL1642137

SMILES CCOC(=O)N1CCCOc2cc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)ccc12

InChI Key InChIKey=RXXOBMLZTZLIBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333563   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333563(3-[5-Chloro-4-(2-fluoro-6-methylcarbamoyl-phenylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of insulin receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333563(3-[5-Chloro-4-(2-fluoro-6-methylcarbamoyl-phenylam...)
Affinity DataIC50: 36nMAssay Description:Inhibition of c-Met expressed in human GTL-16 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333563(3-[5-Chloro-4-(2-fluoro-6-methylcarbamoyl-phenylam...)
Affinity DataIC50: 25nMAssay Description:Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed