BDBM50333567 2-[5-Chloro-2-(9-ethyl-6,7,8,9-tetrahydro-5-oxa-9-aza-benzocyclohepten-3-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-benzamide::CHEMBL1642141

SMILES CCN1CCCOc2cc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)ccc12

InChI Key InChIKey=LJLGXYINGWGHHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333567   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333567(2-[5-Chloro-2-(9-ethyl-6,7,8,9-tetrahydro-5-oxa-9-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of insulin receptor after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333567(2-[5-Chloro-2-(9-ethyl-6,7,8,9-tetrahydro-5-oxa-9-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of c-Met expressed in human GTL-16 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50333567(2-[5-Chloro-2-(9-ethyl-6,7,8,9-tetrahydro-5-oxa-9-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed