BDBM50333643 (2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-(1-hydroxycyclopropyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1642524

SMILES O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C1(O)CC1)c1ccc(Cl)c(Cc2ncc(s2)-c2ccco2)c1

InChI Key InChIKey=MMQLBXHQPGPQNJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50333643   

TargetSodium/glucose cotransporter 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50333643((2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thi...)
Affinity DataIC50: 48.9nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed