BDBM50333783 (E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)-but-2-ene dibromide::4-(aminocarbonyl)-1-((2E)-4-{4-[(E)-(hydroxyimino)methyl]pyridinium-1-yl}but-2-enyl)pyridinium dibromide::4-carbamoyl-1-((E)-4-(4-((E)-(hydroxyimino)methyl)pyridinium-1-yl)but-2-enyl)pyridinium bromide::4-carbamoyl-1-(4-(4-((E)-(hydroxyimino)methyl)pyridinium-1-yl)but-2-enyl)pyridinium bromide::CHEMBL238977

SMILES NC(=O)c1cc[n+](C\C=C\C[n+]2ccc(CN=O)cc2)cc1

InChI Key InChIKey=QAFWIALANDZEHZ-UHFFFAOYSA-O

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333783   

TargetAcetylcholinesterase(Human)
Institute For Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.00E+4nMAssay Description:Reactivation of OP compound induced inhibition of AChE in human erythrocytes using ATCh as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Institute For Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.00E+4nMAssay Description:Reversible inhibition of human erythrocytic AChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Institute For Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataIC50: 5.66E+5nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCholinesterase(Human)
Institute For Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.10E+5nMAssay Description:Reactivation of OP compound induced inhibition of BChE in human plasma using ATCh as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Institute For Medical Research and Occupational Health

Curated by ChEMBL
LigandPNGBDBM50333783((E)-1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomet...)
Affinity DataKi:  9.10E+5nMAssay Description:Reversible inhibition of human plasma BChE using acetylthiocholine iodide as substrate by Ellman spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed