BDBM50333861 (R)-2-(7-(5-chloro-N-methylthiophene-2-sulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643801

SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)c1ccc(Cl)s1

InChI Key InChIKey=UVDYNJXUCJCCQN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333861   

TargetProstaglandin D2 receptor 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333861((R)-2-(7-(5-chloro-N-methylthiophene-2-sulfonamido...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333861((R)-2-(7-(5-chloro-N-methylthiophene-2-sulfonamido...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333861((R)-2-(7-(5-chloro-N-methylthiophene-2-sulfonamido...)
Affinity DataKi:  283nMAssay Description:Binding affinity to prostanoid DP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333861((R)-2-(7-(5-chloro-N-methylthiophene-2-sulfonamido...)
Affinity DataKi:  2.84E+3nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed