BDBM50333950 (S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-methyl-amino)-4-(2-methoxy-ethoxy)-2,15-dioxo-11-oxa-3,14-diaza-tricyclo[14.3.1.1*5,9*]henicosa-1(20),5,7,9(21),16,18-hexaen-13-yl]-ethyl}-N-isobutyl-3-methyl-butyramide::CHEMBL1644468

SMILES COCCOC1NC(=O)c2cc(cc(c2)C(=O)N[C@@H](COCc2cccc1c2)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)C)N(C)S(C)(=O)=O

InChI Key InChIKey=PVPCBXKRPVESEX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333950   

TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed