BDBM50333958 CHEMBL1644475::exo-(1R,5S)-3-(2-chlorophenoxy)-8-azabicyclo[3.2.1]octane

SMILES Clc1ccccc1O[C@H]1C[C@@H]2CC[C@H](C1)N2

InChI Key InChIKey=MJWXDPDEDHUUJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333958   

LigandPNGBDBM50333958(exo-(1R,5S)-3-(2-chlorophenoxy)-8-azabicyclo[3.2.1...)
Affinity DataIC50: 188nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333958(exo-(1R,5S)-3-(2-chlorophenoxy)-8-azabicyclo[3.2.1...)
Affinity DataIC50: 881nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333958(exo-(1R,5S)-3-(2-chlorophenoxy)-8-azabicyclo[3.2.1...)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed