BDBM50333966 CHEMBL1644483::exo-3-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)benzonitrile

SMILES N#Cc1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1

InChI Key InChIKey=OGKOSOTXSHSDIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333966   

LigandPNGBDBM50333966(exo-3-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)be...)
Affinity DataIC50: 126nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333966(exo-3-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)be...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333966(exo-3-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)be...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed