BDBM50333974 CHEMBL1644607::exo-3'-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)biphenyl-3-carbonitrile

SMILES N#Cc1cccc(c1)-c1cccc(O[C@H]2C[C@@H]3CC[C@H](C2)N3)c1

InChI Key InChIKey=GSHCBUDNKQJONH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50333974   

LigandPNGBDBM50333974(exo-3'-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)b...)
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333974(exo-3'-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)b...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
LigandPNGBDBM50333974(exo-3'-((1R,5S)-8-azabicyclo[3.2.1]octan-3-yloxy)b...)
Affinity DataIC50: 481nMAssay Description:Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed