BDBM50334057 5-chloro-6-(1H-indol-7-yl)-2,2,3,3,8-pentamethyl-2,3-dihydroquinolin-4(1H)-one::CHEMBL1644764

SMILES Cc1cc(c(Cl)c2C(=O)C(C)(C)C(C)(C)Nc12)-c1cccc2cc[nH]c12

InChI Key InChIKey=JQKOMAQFUWNONV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334057   

TargetGlucocorticoid receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334057(5-chloro-6-(1H-indol-7-yl)-2,2,3,3,8-pentamethyl-2...)
Affinity DataKi:  416nMAssay Description:Displacement of radiolabeled Dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334057(5-chloro-6-(1H-indol-7-yl)-2,2,3,3,8-pentamethyl-2...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity to progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed