BDBM50334377 2beta-(3-Methylisoxazol-5-yl)-3alpha-(4-chlorophenyl)-8-thiabicyclo[3.2.1]octane::CHEMBL1643654

SMILES Cc1cc(on1)[C@@H]1C2CCC(C[C@H]1c1ccc(Cl)cc1)S2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334377   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50334377(2beta-(3-Methylisoxazol-5-yl)-3alpha-(4-chlorophen...)
Affinity DataIC50: 32.7nMAssay Description:Displacement of [3H]WIN35428 from human DAT transfected cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50334377(2beta-(3-Methylisoxazol-5-yl)-3alpha-(4-chlorophen...)
Affinity DataIC50: 7.00E+3nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed