BDBM50334456 CHEMBL1643902::N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopentacyclo[5.4.0.02,6.03,10.05,9]undecane

SMILES CN(CCc1cccc(F)c1)[C@@H]1C2C3CC4C5CC(C2C35)C14

InChI Key

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50334456   

TargetSodium-dependent dopamine transporter(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of (+)-[3H]pentazocine from sigma 1 receptor in rat PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  2.07E+3nMAssay Description:Inhibition of Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  4.45E+3nMAssay Description:Inhibition of H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  4.45E+3nMAssay Description:Inhibition of histamine H2 receptor (unknown origin) by PDSP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi:  6.09E+3nMAssay Description:Inhibition of 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50334456(N-(2-(3'-Fluorophenyl)ethyl)-N-methyl-8-aminopenta...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of histamine H1 receptor (unknown origin) by PDSP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed