BDBM50334595 5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)pyrimidine-2,4-diamine::CHEMBL1642253

SMILES COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccc(cc2OC)N2CCOCC2)n1)N1CCOCC1

InChI Key InChIKey=DNVHYSBDUBOLFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334595   

TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 120nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334595(5-chloro-N2,N4-bis(2-methoxy-4-morpholinophenyl)py...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed