BDBM50334596 7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)pyrimidin-2-ylamino)-1-ethyl-6-methoxy-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one::CHEMBL1642254

SMILES CCN1c2ccc(Nc3ncc(Cl)c(Nc4ccc(cc4OC)N4CCOCC4)n3)c(OC)c2CCCC1=O

InChI Key InChIKey=IZIDFGQXIWTIKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334596   

TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 175nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 34nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334596(7-(5-chloro-4-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed