BDBM50334599 5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-N4-(2-methoxy-4-morpholinophenyl)pyrimidine-2,4-diamine::CHEMBL1642257

SMILES COc1cc2CCN(CCS(C)(=O)=O)CCc2cc1Nc1ncc(Cl)c(Nc2ccc(cc2OC)N2CCOCC2)n1

InChI Key InChIKey=HTOHTWMWPRZGEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334599   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334599(5-chloro-N2-(8-methoxy-3-(2-(methylsulfonyl)ethyl)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed