BDBM50334601 2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2-ylamino)-8-methoxy-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-N,N-dimethylacetamide::CHEMBL1642260

SMILES COc1ccccc1Nc1nc(Nc2cc3CCN(CC(=O)N(C)C)CCc3cc2OC)ncc1Cl

InChI Key InChIKey=JVCFOBYUGHIPJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334601   

TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 62nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334601(2-(7-(5-chloro-4-(2-methoxyphenylamino)pyrimidin-2...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed