BDBM50334602 4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)pyrimidin-4-ylamino)-3-methoxybenzamide::CHEMBL1642261

SMILES COc1cc2CCN(CC(=O)N(C)C)CCc2cc1Nc1ncc(Cl)c(Nc2ccc(cc2OC)C(N)=O)n1

InChI Key InChIKey=NJPLUFOJYZAGOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334602   

TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of ALK by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50334602(4-(5-chloro-2-(3-(2-(dimethylamino)-2-oxoethyl)-8-...)
Affinity DataIC50: 573nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed