BDBM50334632 (S)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[5,4-b]pyridin-2-yl)phenyl)ethyl)acetamide::CHEMBL1642545

SMILES CNc1nc2sc(nc2c2n(C)cnc12)-c1cccc(c1)[C@H](C)NC(C)=O

InChI Key InChIKey=APRXYRORERCWAV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334632   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334632((S)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4...)
Affinity DataIC50: 6nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334632((S)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4...)
Affinity DataIC50: 9nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334632((S)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4...)
Affinity DataIC50: 230nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334632((S)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4...)
Affinity DataIC50: 430nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed