BDBM50334634 (S)-N-(1-(3-(5-amino-8-methyl-8H-imidazo[4,5-d]thiazolo[5,4-b]pyridin-2-yl)phenyl)ethyl)acetamide::CHEMBL1642547

SMILES C[C@H](NC(C)=O)c1cccc(c1)-c1nc2c(nc(N)c3ncn(C)c23)s1

InChI Key InChIKey=DYHUWKGUGOWLTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334634   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334634((S)-N-(1-(3-(5-amino-8-methyl-8H-imidazo[4,5-d]thi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50334634((S)-N-(1-(3-(5-amino-8-methyl-8H-imidazo[4,5-d]thi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human IKK2-mediated GST-IkappaBalpha protein fusion phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed