BDBM50334733 3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1Hindazol-5-amine HCl::CHEMBL1642886

SMILES CC(C)c1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(NC3CCNCC3)cc12

InChI Key InChIKey=JHVNSHBHMRPFIN-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50334733   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  859nMAssay Description:Binding affinity to 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to 5-HT1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  1.76E+3nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  1.77E+3nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  2.73E+3nMAssay Description:Binding affinity to 5-HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi:  3.22E+3nMAssay Description:Binding affinity to 5-HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334733(3-(4-Isopropylphenylsulfonyl)-N-(piperidin-4-yl)-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed