BDBM50334735 3-(4-Methoxyphenylsulfonyl)-N-(piperidin-4-yl)-1Hindazol-5-amine HCl::CHEMBL1642888

SMILES COc1ccc(cc1)S(=O)(=O)c1n[nH]c2ccc(NC3CCNCC3)cc12

InChI Key InChIKey=UUSYXRWQMSIPSN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334735   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334735(3-(4-Methoxyphenylsulfonyl)-N-(piperidin-4-yl)-1Hi...)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334735(3-(4-Methoxyphenylsulfonyl)-N-(piperidin-4-yl)-1Hi...)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed