BDBM50335193 6-Methyl-N-[3-[[(2,2,3,3,3-pentafluoropropyl)amino]methyl]-5-isothiazolyl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amineHydrochloride::CHEMBL1650550

SMILES Cc1cn2c(cnc2c(Nc2cc(CNCC(F)(F)C(F)(F)F)ns2)n1)-c1cn[nH]c1

InChI Key InChIKey=JQTJXXKLVJKNLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50335193   

TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50335193(6-Methyl-N-[3-[[(2,2,3,3,3-pentafluoropropyl)amino...)
Affinity DataIC50: 51nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as inhibition of histone H3 phosphorylation by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed