BDBM50335466 1-(4-(5-butoxybenzofuran-2-yl)-3-chlorobenzyl)azetidine-3-carboxylic acid::CHEMBL1651714

SMILES CCCCOc1ccc2oc(cc2c1)-c1ccc(CN2CC(C2)C(O)=O)cc1Cl

InChI Key InChIKey=KAEUWGJEROCSNU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335466   

TargetSphingosine 1-phosphate receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335466(1-(4-(5-butoxybenzofuran-2-yl)-3-chlorobenzyl)azet...)
Affinity DataEC50:  158nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335466(1-(4-(5-butoxybenzofuran-2-yl)-3-chlorobenzyl)azet...)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed