BDBM50335496 4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfonate::CHEMBL1651846

SMILES CS(=O)(=O)Oc1ccc(cc1)S(=O)(=O)CC1CS1

InChI Key InChIKey=LWHDLJDNHJFUSI-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50335496   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  390nMAssay Description:Inhibition of MMP2 by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  480nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of human recombinant MMP9 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of human recombinant MMP7 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335496(4-(Thiiran-2-ylmethylsulfonyl)phenyl methanesulfon...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain by substrate hydrolysis based fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed