BDBM50335805 4-Fluoro-N-(8-hydroxyquinolin-5-yl)benzenesulfonamide::CHEMBL1650637

SMILES Oc1ccc(NS(=O)(=O)c2ccc(F)cc2)c2cccnc12

InChI Key InChIKey=ZPLJVEYEKBDFPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335805   

Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50335805(4-Fluoro-N-(8-hydroxyquinolin-5-yl)benzenesulfonam...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50335805(4-Fluoro-N-(8-hydroxyquinolin-5-yl)benzenesulfonam...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human MMP2 using thiopeptide as substrate preincubated for 30 mins followed by substrate addition and measured every mins f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50335805(4-Fluoro-N-(8-hydroxyquinolin-5-yl)benzenesulfonam...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human MMP9 using thiopeptide as substrate preincubated for 30 mins followed by substrate addition and measured every min fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed