BDBM50336063 4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(((2S,4R)-4-fluoropyrrolidin-2-yl)methyl)-N-methylbenzamide::CHEMBL1669331

SMILES CN(C[C@@H]1C[C@@H](F)CN1)C(=O)c1ccc(cc1)-c1cnc2ccc(NCC3CC3)nn12

InChI Key InChIKey=QBQKDVXZHPPBDJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336063   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Daiichi Sankyo

Curated by ChEMBL

LigandBDBM50336063(4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridaz...)Copy SMILESCopy InChI

Affinity DataIC50: 42nMAssay Description:Inhibition of purified His-tagged IKK-beta after 15 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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