BDBM50336066 CHEMBL1669405::N-ethyl-N-methyl-2-(3-(pyrazin-2-ylmethyl)-1H-inden-2-yl)ethanamine

SMILES CCN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1

InChI Key InChIKey=SZKXEXNSYILRKM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336066   

TargetHistamine H1 receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50336066(N-ethyl-N-methyl-2-(3-(pyrazin-2-ylmethyl)-1H-inde...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50336066(N-ethyl-N-methyl-2-(3-(pyrazin-2-ylmethyl)-1H-inde...)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50336066(N-ethyl-N-methyl-2-(3-(pyrazin-2-ylmethyl)-1H-inde...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed