BDBM50336411 4-amino-2,7-dimethyl-N-(1H-pyrazol-5-yl)quinazoline-8-carboxamide::CHEMBL1668265

SMILES Cc1nc(N)c2ccc(C)c(C(=O)Nc3ccn[nH]3)c2n1

InChI Key InChIKey=JBGZHQNGVBHRRI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336411   

TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50336411(4-amino-2,7-dimethyl-N-(1H-pyrazol-5-yl)quinazolin...)
Affinity DataKi:  984nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50336411(4-amino-2,7-dimethyl-N-(1H-pyrazol-5-yl)quinazolin...)
Affinity DataKi:  4.55E+3nMAssay Description:Inhibition of PI3Kalpha by fluorescene polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed