BDBM50336460 (S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5,6,7,8,11,12,13,14-octahydrobenzo[14]annulene::CHEMBL1668420

SMILES COc1cc(O)c2c(c1)C=CCCCC(=O)C=CC[C@H](C)OC2=O

InChI Key InChIKey=HRKYCRIVTWSVJU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50336460   

TargetVascular endothelial growth factor receptor 3(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in insect cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant VEGFR1 expressed in Sf9 cells after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336460((S,9E,15Z)-2-ethyl-4,7-dimethyl-5,11-dimethylene-5...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MEK1 expressed in insect cells after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed