BDBM50336464 (3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione::CHEMBL1668416

SMILES COc1cc(O)c2c(c1)\C=C/CCCC(=O)C[C@H](Cl)C[C@H](C)OC2=O

InChI Key InChIKey=HEECBHPHEJLGSX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336464   

TargetVascular endothelial growth factor receptor 3(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant VEGFR3 in cell free system after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant c-kit kinase in cell free system after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human recombinant PDGFRalpha in cell free system after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant FLT-3 kinase expressed in insect cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National University of Ireland

Curated by ChEMBL
LigandPNGBDBM50336464((3S,5R,Z)-5-chloro-16-hydroxy-14-methoxy-3-methyl-...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed