BDBM50336853 (R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672304

SMILES CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key InChIKey=BVBIAGFWBHXIBM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336853   

TargetD(3) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336853((R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydr...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]domperidone from human cloned dopamine D3 receptor high binding site expressed in mouse CCL1-3 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336853((R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydr...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336853((R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydr...)
Affinity DataKi:  990nMAssay Description:Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336853((R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydr...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336853((R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydr...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed