BDBM50336857 11-hydroxy-N-(3-fluoropropyl)aporphine::CHEMBL1672302

SMILES Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12

InChI Key InChIKey=VAURMGBDDSMOJD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336857   

TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336857(11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336857(11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...)
Affinity DataKi:  860nMAssay Description:Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336857(11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336857(11-hydroxy-N-(3-fluoropropyl)aporphine | CHEMBL167...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]domperidone from human cloned dopamine D3 receptor expressed in mouse CCL1-3 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed