BDBM50336862 CHEMBL1672311::N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine

SMILES CCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1cccc(O)c-31

InChI Key InChIKey=LODBNYQJHVOXNX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336862   

TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336862(N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]domperidone from dopamine D2 receptor high binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336862(N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]domperidone from rat cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336862(N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine...)
Affinity DataKi:  400nMAssay Description:Displacement of [3H]SCH23390 from dopamine D2 receptor low binding site in Sprague-Dawley rat striatum by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50336862(N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D1 receptor low binding site by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed