BDBM50336922 3-chloro-5-(5-chloro-1-propyl-1H-benzo[d]imidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amine::CHEMBL1672537

SMILES CCCn1c(nc2cc(Cl)ccc12)-c1cnc(Nc2ccc(C)nc2)c(Cl)c1

InChI Key InChIKey=BDBFKUUNGAKBKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336922   

TargetMetabotropic glutamate receptor 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336922(3-chloro-5-(5-chloro-1-propyl-1H-benzo[d]imidazol-...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed