BDBM50336923 (R)-(5-chloro-6-(4-chlorophenylamino)pyridin-3-yl)(2-ethylpiperidin-1-yl)methanone::CHEMBL1672435

SMILES CC[C@@H]1CCCCN1C(=O)c1cnc(Nc2ccc(Cl)cc2)c(Cl)c1

InChI Key InChIKey=COGYAXFYJYPHMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336923   

TargetMetabotropic glutamate receptor 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336923((R)-(5-chloro-6-(4-chlorophenylamino)pyridin-3-yl)...)
Affinity DataIC50: 64nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed