BDBM50336927 3-chloro-5-(6-chloro-1-propyl-1H-benzo[d]imidazol-2-yl)-N-(6-methylpyridin-3-yl)pyridin-2-amine::CHEMBL1672538

SMILES CCCn1c(nc2ccc(Cl)cc12)-c1cnc(Nc2ccc(C)nc2)c(Cl)c1

InChI Key InChIKey=GURJCURQGMVSSN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336927   

TargetMetabotropic glutamate receptor 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336927(3-chloro-5-(6-chloro-1-propyl-1H-benzo[d]imidazol-...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human mGlu5 receptor assessed as inhibition of glutamate-induced calcium flux by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed