BDBM50336971 5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole::CHEMBL1672583

SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(I)cc1)C(F)(F)F

InChI Key InChIKey=NIUAGEVCVWHMTA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336971   

TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in mouse LPS-stimulated RAW264.7 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse purified COX2 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
TBA

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of ovine purified COX1 after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50336971(5-(4-iodophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(t...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed