BDBM50336980 CHEMBL1672633::N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyrazin-2-yl]cyclopropane-carboxamide

SMILES Fc1cnccc1-c1ncc(NC(=O)C2CC2)nc1-c1cnco1

InChI Key InChIKey=QRZYIOBBNKOVAA-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50336980   

TargetAdenosine receptor A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336980(N-[5-(3-Fluoropyridin-4-yl)-6-(1,3-oxazol-5-yl)pyr...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed