BDBM50336989 CHEMBL1672619::N-[6-(5-Methyl-2-furyl)-5-pyridin-4-ylpyrazin-2-yl]cyclopropanecarboxamide

SMILES Cc1ccc(o1)-c1nc(NC(=O)C2CC2)cnc1-c1ccncc1

InChI Key InChIKey=IATOZURPNIOIDD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336989   

TargetAdenosine receptor A2a(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336989(N-[6-(5-Methyl-2-furyl)-5-pyridin-4-ylpyrazin-2-yl...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336989(N-[6-(5-Methyl-2-furyl)-5-pyridin-4-ylpyrazin-2-yl...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336989(N-[6-(5-Methyl-2-furyl)-5-pyridin-4-ylpyrazin-2-yl...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336989(N-[6-(5-Methyl-2-furyl)-5-pyridin-4-ylpyrazin-2-yl...)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in HeLa cells after 3 hrs by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed