BDBM50337031 5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-dione::CHEMBL1672755

SMILES CCc1cc(=O)oc2[nH]c(=S)[nH]c(=O)c12

InChI Key InChIKey=AGWCOWNJAYMSIC-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337031   

TargetHydroxycarboxylic acid receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337031(5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-...)
Affinity DataEC50:  470nMAssay Description:Agonist activity at human recombinant GPR109a expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337031(5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-...)
Affinity DataEC50:  470nMAssay Description:Agonist activity at human HM74AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFree fatty acid receptor 3(Human)
Mansoura University

Curated by ChEMBL
LigandPNGBDBM50337031(5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at FFA3 (unknown origin) expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337031(5-ethyl-2-mercapto-3H-pyrano[2,3-d]pyrimidine-4,7-...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human HCA2 expressed in human Flp-In-293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed