BDBM50337051 (2S,3R,4R,5S,6R,E)-2-(3-((5-(but-2-en-2-yl)thiazol-2-yl)methyl)-4-chlorophenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1672779

SMILES C\C=C(/C)c1cnc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)s1

InChI Key InChIKey=SHPLXKFUHIGDKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337051   

TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337051((2S,3R,4R,5S,6R,E)-2-(3-((5-(but-2-en-2-yl)thiazol...)
Affinity DataIC50: 4.69nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed