BDBM50337084 2-((5-(Thiophen-3-yl)thiazol-2-yl)methyl)-4-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yl)benzonitrile::CHEMBL1672812

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(C#N)c(Cc2ncc(s2)-c2ccsc2)c1

InChI Key InChIKey=LXXXIDBLCWDSKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337084   

TargetSodium/glucose cotransporter 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50337084(2-((5-(Thiophen-3-yl)thiazol-2-yl)methyl)-4-((2S,3...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed