BDBM50337312 5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-indazole::CHEMBL1682343

SMILES C(Cc1cn(nn1)-c1ccc2[nH]ncc2c1)Cc1ccccc1

InChI Key InChIKey=DCBGVRDAEOIKPQ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337312   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi:  62nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi:  528nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi:  644nMAssay Description:Inhibition of JAK2 after 1 hr using biotinylated PDKtide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi: >1.80E+3nMAssay Description:Inhibition of EGFR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi:  1.93E+3nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4 after 1 hr using biotinylated L15 peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi: >8.57E+3nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337312(5-(4-(3-phenylpropyl)-1H-1,2,3-triazol-1-yl)-1H-in...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed