BDBM50337313 5-(1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682344

SMILES c1[nH]nnc1-c1ccc2n[nH]cc2c1

InChI Key InChIKey=MCXNJEWRZUGGHR-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50337313   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  209nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  448nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  493nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  1.45E+3nMAssay Description:Inhibition of JAK2 after 1 hr using biotinylated PDKtide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  2.22E+3nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  3.55E+3nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337313(5-(1H-1,2,3-triazol-4-yl)-1H-indazole | CHEMBL1682...)
Affinity DataKi:  6.99E+4nMAssay Description:Inhibition of Pak4 after 1 hr using biotinylated L15 peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed