BDBM50337316 5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682347

SMILES Clc1ccccc1Cn1cc(nn1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=ONQWJQFYUGAKLG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337316   

TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337316(5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  45nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337316(5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  97nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337316(5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  553nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337316(5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi: >1.45E+3nMAssay Description:Inhibition of JAK2 after 1 hr using biotinylated PDKtide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337316(5-(1-(2-chlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  4.15E+3nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed