BDBM50337319 5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682350

SMILES Fc1ccccc1Cn1cc(nn1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=NRDHAKDUAFEDCQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337319   

TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  16nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  91nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  285nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi: >915nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337319(5-(1-(2-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of Pak4 after 1 hr using biotinylated L15 peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed